The general asymmetric five-parameter logistic model for describing dose-response relationships.

meL.2(x, b, e)

meL.3(x, b, d, e)

meL.4(x, b, c, d, e)

meL.5(x, b, c, d, e, f)

Arguments

x

numeric dose vector.

b

steepness

e

ED50

d

upper limit

c

lower limit

f

asymmetry

Details

The default arguments yields the five-parameter logistic mean function given by the expression $$ f(x) = c + \frac{d-c}{(1+\exp(b(x - e)))^f}$$ The model is sometimes referred to as the Boltzmann model.